Wof is the most accurate statement regarding digoxin

A. Increases vagal tone and decreases AV node conduction

B. Decreases moality in patients with congestive hea failure with normal sinus rhythm

C. Lengthens the action potential and increases the refractoriness of the hea

D. Useful in the treatment of Wolff-Parkinson-White syndrome

Correct Answer: Increases vagal tone and decreases AV node conduction

Description: CARDIAC GLYCOSIDES PHARMACOLOGICAL ACTIONS Hea:- Hea rate:-Hea rate is decreased by digitalis. Bradycardia is more marked in CHF patients because improved circulation (due to positive inotropic action) restores the diminished vagal tone and abolishes sympathetic overactivity. In addition, digitalis slows the hea by vagal and extravagal actions. Vagal tone:- is increased reflexly by sensitization of baroreceptors, as well as by stimulation of vagal centre. Extravagal:- A direct depressant action on SA and A-V nodes. This component of bradycardia is not reversed by atropine. Ref:- kd tripathi; pg num:-512,513

Category: Pharmacology

Share:

← Previous MCQ

Next MCQ →

Get More

Subject Mock Tests

Practice with over 200,000 questions from various medical subjects and improve your knowledge.

Attempt a mock test now

Mock Exam

Take an exam with 100 random questions selected from all subjects to test your knowledge.

Coming Soon

Get More

Subject Mock Tests

Try practicing mock tests with over 200,000 questions from various medical subjects.

Attempt a mock test now

Mock Exam

Attempt an exam of 100 questions randomly chosen from all subjects.

Coming Soon