Decarboxylation reactions require
Correct Answer: Thiamine
Description: Pyruvate dehydrogenase: The co-enzyme form is thiamine pyrophosphate (TPP). It is used in oxidative decarboxylation of alpha-keto acids, e.g. pyruvate dehydrogenase catalyzes the breakdown of pyruvate, to acetyl CoA and carbon dioxide (see Fig. 9.22).Alpha-ketoglutarate dehydrogenase: an analogous biochemical reaction that requires TPP is the oxidative decarboxylation of alpha-ketoglutarate to succinyl CoARef: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 478
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