A 45 yr old patient presents with fever, night sweats, weight loss. On X ray a mass in apical lobe of lung is seen. On histopathology found to have caseous necrosis. What is the underlying process?
Correct Answer: Hypersensitivity reaction with modified macrophages, lymphocytes and giant cells
Description: Ans. (b) Hypersensitivity reaction with modified macrophages, lymphocytes and giant cells(Ref: Robbins 9th/pg 208-211; 8th/pg 204-208)The given clinical features and radiological Findings are suggestive of Tuberculosis in which histopathology of the affected organ shows granuloma, that consists of modified macrophages, lymphocytes and giant cells.
Category:
Pathology
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