Reverse transcriptase is a RNA dependent DNA polymerase. Which of these use it?
Correct Answer: Hepatitis B virus
Description: Ans. (b) Hepatitis B virus Set ot te,, DNA polymerase of HBV has both DNA-dependent DNA polymerase and RNA-dependent reverse transcriptase activities. Not Instead of DNA replication directly from a DNA template, hepadnaviruses rely on reverse transcription (effected by the DNA polymerase) of minus-strand DNA from a "pregenomic" RNA intermediate. Then plus-strand DNA is transcribed from the minus strand DNA template by the DNA-dependent DNA polymerase and conveed in the hepatocyte nucleus to a covalently closed circular DNA, which serves as a template for messenger RNA and pregenomic RNA.
Category:
Microbiology
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