Which of the following is seen in eosinophil granules?
Correct Answer: Major basic protein
Description: Eosinophils are abundant in immune reactions mediated by IgE and in parasitic infections. A chemokine that is especially impoant for eosinophil recruitment is eotaxin. Eosinophils have granules that contain major basic protein, a highly cationic protein that is toxic to parasites but also causes lysis of mammalian epithelial cells. Ref: Robbins 8th edition, Chapter 2.
Category:
Pathology
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