Inhibition of which of the following vitamin is caused by Isoniazid?
Correct Answer: Pyridoxine
Description: Isoniazid inhibits pyridoxal phosphokinase You know that the biologically active form of pyridoxine is pyridoxal phosphate.Thus, Isoniazid inhibits the formation of the active form of B6. Vitamin B6 (pyridoxine) supplementation during isoniazid (INH) therapy is necessary in some patients to prevent the development of peripheral neuropathy. As Vit B6 (PLP) is required for Niacin synthesis from tryptophan, hence Isoniazid therapy also causes Niacin deficiency.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now