Which of the following clinical findings is more likely to be associated with acute rather than chronic glomerulonephritis?
Correct Answer: Preservation of concentrating ability
Description: Acute glomerulonephritis is more likely to be associated with preservation of concentrating ability than chronic glomerulonephritis, in which tubular dysfunction is present. Osteomalacia, the inability to mineralize osteoid, is more likely to occur in chronic glomerulonephritis because of the loss of vitamin D synthesis in the tubules. Increased anion gap metabolic acidosis is more likely to occur in chronic glomerulonephritis because tubular function and the ability to excrete a hydrogen load are disturbed. Oliguria occurs in both acute and chronic glomerulonephritis. Casts in the urine are present in both diseases. However, red blood cell and white blood cell casts are more likely to be present in acute glomerulonephritis, whereas waxy and I broadcasts are more likely in chronic glomerulonephritis. Ref - Harrison's internal medicine 20e pg 2136 ,2105
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