A perimenopausal woman on Pap smear has repoed ASCUS (atypical squamous cell of unknown significance). Next line of management is:

Correct Answer: Colposcopy
Description: In Bethesda system, the most common cytological abnormality is atypical squamous cells (ASC). ASC is fuher divided into ASCUS (atypical squamous cell of unknown significance) and ASC-H (atypical squamous cells where HSIL cannot be ruled out). The risk of progression of ASCUS to CIN is 5%. These patients should be followed up with: 1. HPV DNA testing 2. Immediate colposcopy 3. Repeated cytology at 6-12 months Ref: GYANECOLOGICAL DIAGNOSIS ; Novak, 15th edition, page 587q
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