A patient with chronic liver disease developed spider naevi dilation on chest. It may be due to excess of the following hormone:
Correct Answer: Estrogen
Description: The spider nevus, or spider angioma, is the most representative and classic vascular lesion of chronic liver disease. Clinically, it has a central aeriole from which numerous small, twisted vessels radiate. Vascular spider nevi and palmar erythema are generally attributed to estrogen excess, paicularly because they also occur during pregnancy and because estrogens have an enlarging, dilating effect on the spiral aerioles of the endometrium. This would also explain spider nevi in men receiving estrogen therapy for prostatic cancer. Ref: Johnston G.A., Graham-Brown R.A. (2012). Chapter 150. The Skin and Disorders of the Alimentary Tract, the Hepatobiliary System, the Kidney, and the Cardiopulmonary System. In L.A. Goldsmith, S.I. Katz, B.A. Gilchrest, A.S. Paller, D.J. Leffell, N.A. Dallas (Eds), Fitzpatrick's Dermatology in General Medicine, 8e.
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