Non pitting edema is seen in ?

Correct Answer: Myxedema
Description: A consequence of prolonged hypothyroidism is increased dermal infiltration of glycosaminoglycans (mucopolysaccharides, hyaluronic acid and chondroitin sulphate) which traps water, giving rise to skin thickening without pitting (myxedema). Typical features include a puffy face with edematous eyelids and nonpitting pretibial edema. Reference : page 2291 Harrison's Principles of Internal Medicine 19th edition and page 743 Davidson's Principles and practice of Medicine 22nd edition
Category: Medicine
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