Which of the following is the main factor for the ductal closure postnatally
Correct Answer: Increase in paial pressure of oxygen (PaO2)
Description: Oxygen is the most impoant controlling ductal closure. Note: Gestational age also appears to play an impoant role; the ductus of a premature infant is less responsive to oxygen, even though its muscular is developed. Hence, patent ductus aeriosus (PDA) is more common in premature infants. Ref: Nelson textbook of pediatrics 21st edition Pgno: 2345
Category:
Pediatrics
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