Obstructive jaundice may be seen as a side effect of therapy with –
Correct Answer: Chlorpromazine
Description: cholestatic jaundice is seen with phenothiazine group of antipsychotics-chlorpromazine,triflupromazine,Thioridazine,fluphenazine It occurs between 2-4 weeks of staing the therapy and calls for withdrawal of drug. It is rare with haloperidol. 2.Other drugs causing cholestatic jaundice are-prochlorperazine,erythromycin estolate,anabolic and contraceptive steroids. Ref:KDtripathi pg no. 445.Harrison 20th edition pg no. 280 table:45-3
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