Palivizumab is a humanized monoclonal antibody. For which of the following conditions has it been approved for?
Correct Answer: Respiratory syncytial virus
Description: d. Respiratory syncytial virus(Ref: Nelson 20/e p 1608)Drug Use in RSV infectionPalivhzumabIt is a monoclonal antibody licensed for prophylaxis in high-risk infants during the RSV season, and does prevent about half of the expected hospitalizations in that population.RibavirinIt is an antiviral agent delivered as an aerosol that showed a modest beneficial effect on the course of RSV pneumonia, with some reduction in the duration of both mechanical ventilation and hospitalization. However, latest studies have failed to document a clear beneficial effect of ribavirin, and therefore this drug is no longer used for routine therapy of RSV disease.
Category:
Pediatrics
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