All of the following statements about hyponatremia are true, except:
Correct Answer: Pseudohyponatremia is associated with low plasma osmolality
Description: Pseudohyponatremia is associated with normal serum osmolarity. In this condition the aqueous fraction of plasma is decreased and the paiculate fraction is increased. This can result from hyperlipidemia (TG>1500mg/dl), hypercholesterolemia or hyperprotenemia (as in multiple myeloma, waldenstroms macroglobulinemia, administration of intravenous immunoglobulin) Ref: Nephrology in 30 Days By Robe F. Reilly, Mark A. Perazella, page 38; Goldfrank's toxicologic emergencies By Lewis R. Goldfrank, Neal Flomenbaum, page 287; Goldfrank's toxicologic emergencies By Lewis R. Goldfrank, Neal Flomenbaum, page 288; Textbook Of Pharmacology By Seth 3rd edn, page29
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