The following group of tests should be done to optimise graft uptake in bone marrow transplant:
Correct Answer: HLA matching
Description: Most prospective donors are initially typed for HLA-A and HLA-B loci. Donors identified as potential HLA-A and HLA-B matches are then asked to donate a specimen for DR- loci typing. When a donor is identified as a potential HLA-A and HLA-B and a DR match for a given recipient he is checked for transmissible infectious diseases such as Cytomeggalovirus (CMV) etc. Ref: Hematopoietic Stem Cell Transplantation By Michael R. Bishop, Page 86
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