Vitamin B6 deficiency cause increased excretion of
Correct Answer: Xanthurenic acid
Description: Vit B6 deficiency causes increased excretion of Xanthurenic acid.Pyridoxal phosphate is required for the synthesis of niacin from tryptophan (one vitamin is necessary for synthesis of another vitamin) (Figs17.8 and 17.9). 3-hydroxy kynurenine - 3-hydroxy anthranilic acid (Enzyme Kynureninase). Kynureninase is a PLP dependent enzyme. Hence in vitamin B6 deficiency niacin production is less. Moreover, kynurenine cannot be conveed fuher, which is metabolized to xanthurenic acid and excreted through urine. The metabolic disorders which respond to vitamin B6 therapy are xanthurenic aciduria and homocystinuria.Ref: DM Vasudevan - Textbook of Biochemistry, 6th edition, page no: 397
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now