The most common site of lymphangiosarcoma:
Correct Answer: Post-mastectomy edema of arm
Description: Angiosarcoma: Rare tumour that develops as a complication of long-standing (>10 years) lymphoedema. Stewa and Treves described lymphangiosarcoma of the upper extremity in women with ipsilateral lymphedema after radical mastectomy. (Stewa-Teres syndrome) Clinical Features: Acute worsening of edema. Appearances of sub-cutaneous nodules with propensity towards hemorrhage and ulceration. Treatment: Pre-operative chemotherapy and radiotherapy followed by surgical excision (radical amputation) Associated with poor prognosis. Ref: Sabsiton 20th edition Pgno: 766
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