A 40 year old man having malaise and fatigue, dyspnea on exertion, cardiomegaly on chest X-ray, weight loss of 10 kg, mononeuritis, polyarthritis. The diagnosis is

Correct Answer: Neurosarcoid
Description: (D) Neurosarcoidosis# NEUROSARCOIDOSIS generally occurs only in cases of sarcoidosis with substantial systemic involvement, and signs of neurologic involvement usually are seen in patients known to have active disease.> Strictly neurologic forms are seen in fewer than 10% of patients; a subset has predominantly neuromuscular involvement.> Definitive diagnosis of neurosarcoidosis requires the exclusion of other causes of neuropathy and the identification of noncaseating sarcoid granulomas by histologic analysis of nerve and muscle biopsy specimens.> Neurological involvement: Papilledema (6%); Cranial neuropathy (59%); Peripheral neuropathy (47%); Mononeuropathy (25%); Myopathy (25%); Psychiatric disorders (19%); Cerebellar ataxia (13%) & Hydrocephalus (6%)
Category: Medicine
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