Which of the following drugs when combined erythromycin may cause ventricular arrhythmias?
Correct Answer: Cisapride
Description: - Erythromycin causes inhibition of CYP3A4 enzyme. - As a result of this, level of Cisapride rises in blood - High blood levels of Cisapride causes QT prolongation and leads to Torsades-de-pointes (ventricular arrythmia) so, the combination is avoided.
Category:
Pharmacology
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