Therapeutic index of a drug is a measure of its?
Correct Answer: Safety
Description: Therapeutic Index tells about the safety margin of drug; narrow therapeutic index means unsafe drug. TI : LD50/ED50 *LD50 : lethal dose in 50% of population.*ED50 : effective dose in 50% of population or median effective dose.*LD50 and ED50 can be calculated by plotting a quantal DRC. * In this Quantal DRC, x-axis represents the log dose and y-axis represents the percentage of population responding.* Graded dose response curve tells about the potency and efficacy of a given drug in a paicular individual.
Category:
Pharmacology
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