Which of the following is the drug of choice for the treatment of Syndrome of Inappropriate Antidiuretic Hormone secretion?
Correct Answer: Demeclocycline
Description: Ans. (A) Demeclocycline(Ref: Katzung 10/e p249)SIADH is due to excessive secretion of anti-diuretic hormone. It is diametrically opposite disease to diabetes insipidus. Vasopressin, thiazides and chlorpropamide are used for the treatment of diabetes insipidus whereas demeclocycline is used for SIADH management. Now-a-days, vasopressin receptor antagonists like tolvaptan and conivaptan are preferred for SIADH.
Category:
Pharmacology
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