False about pseudomyxoma peritonei
Correct Answer: Refractory to drugs
Description: Pseudomyxoma peritonei. Pseudomyxoma peritonei describes mucinous ascites arising from a ruptured ovarian or appendiceal adenocarcinoma. In this disease, the peritoneum becomes coated with a mucus-secreting tumor that fills the peritoneal cavity with tenacious semisolid mucus and large, loculated cystic massesThe current treatment of patients with pseudomyxoma peritonei involves resection of as much of the tumor as possible(cytoreduction) and intraperitoneal heated chemotherapy (IPHC). Operative management includes omentectomy, stripping of involved peritoneum, resection of involved organs, and appendectomy, if not previously performed. There should be no residual tumor nodules larger than 2 mm in diameter after resection to facilitate penetration of the chemotherapy into any residual disease. IPHC can be per- formed by an open technique, in which the abdomen is left open to ensure adequate chemotherapy distribution throughout the peritoneal cavity, or a closed technique, in which the abdomen is closed after inflow and outflow cannulas are placed. The latter allows easier maintenance of hypehermia Ref: Sabiston 20th edition Pgno: 1080
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