Which is the following agents is a prerequisite for Prothrombin time (PT) assay?
Correct Answer: Tissue thromboplastin
Description: Prothrombin time (PT) assay: Time (in seconds) needed for plasma to clot after addition of tissue thromboplastin/tissue factor (e.g., brain extract) and Ca2+ ions Assesses the function of the proteins in the extrinsic pathway (factors VII, X, V, II (prothrombin), and fibrinogen) Prolonged PT can result from a deficiency of factor V, VII, X, prothrombin, fibrinogen, presence of an acquired inhibitor that interferes with the extrinsic pathway Kaolin, silica, glass beads are contact activators that trigger the intrinsic pathway and the first two agents are commonly used in paial thromboplastin time (PTT) assay.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now