Intrinsic cell wall defect of RBCs is feature of –
Correct Answer: Paroxysmal nocturnal hemoglobinuria
Description: Paroxysmal nocturnal hemoglobinuria is a disease that results from acquired mutations in the phosphatidylinositol glycan complementation group A gene (PIGA), an enzyme that is essential for the synthesis of ceain membrane associated complement regulatory proteins. Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:642
Category:
Pathology
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