True about Von Willebrand’s disease is all c.Ic cpt :
Correct Answer: Increased platelet aggregation in response to Ristocetin
Description: Answer is C (Increased platelet aggregation in response to Ristocetin) Willebrand disease is characterized by decreased (impaired) platelet aggregation in response to Ristocetin. Deficiency of Factor VIII is characteristic of hemophilia and not VWF disease. VWF however serves as a carrier for factor VIII c and its deficiency therefore leads to decreased availability of factor VIII c at the site of injury. Decaresed level of factor VIII c in the circulation may therefore be explained by a deficiency of vW factor.
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