Mechanism of action of progesterones in the medical management of endometriosis is?
Correct Answer: Deccidualisation and endometrial atrophy
Description: Progesterones act by exeing an anti estrogenic effect and their continuous administration causes decidualisation and endometrial atrophy. The treatment over a period of 6 - 9 months produces a state of pseudopregnancy which ultimately causes regression of disease. It has no effect on ovulation Progestins used commonly are: Norethisterone Dydrogesterone Medroxyrogesterone acetate Mirena IUCD Dienogest
Category:
Gynaecology & Obstetrics
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