Which of the following statements about Pseudohypoprathyroidismistrue-

A. Caused by 'Gain of!ftmction' inherited mutation in Gsa subunit

B. Decreased formation of cyclic GMP is observed

C. Decreased formation of Inositol triphosphate is observed

D. Decreased formation of c-AMP is observed

Correct Answer: Decreased formation of c-AMP is observed

Description: decreased urinary cyclic AMP responses to PTH , presumably with a post -GS alpha defect in adenyl cyclase stimulation ( Harrison 17 pg 2394)

Category: Medicine

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