All of the following statements about ticlodipine are true, EXCEPT:
Correct Answer: It directly interacts with platelet membrane, Gpllb / llla receptors
Description: Ticlopidine is not a Gpllbb/llla receptor blocker, it acts by altering the cell surface receptors on the platelets and inhibits ADP as well as fibrinogen induced platelet aggregation. It prevents fibrinogen binding to platelets without modifying GPllb/llla receptor. Ref: Essentials of Medical Pharmacology, 5th Eedition, Pages 572-3; Current Cardiovascular Drugs By William H. Frishman, Page 128.
Category:
Pharmacology
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