Increase in cytosolic calcium from intracellular storage, during smooth muscle contraction, is/are due to –

Correct Answer: IP3-DAG
Description: The release of Ca++ from intracellular source, that is sarcoplasmic reticulum, is by IP3-DAG second messenger system, whereas the pumping of Ca++ from extracellular space to cytosol is by Ca++ channels. IP3 when bound to its receptors on sarcoplasmic reticulum, causes the release of calcium into sarcoplasm.
Category: Physiology
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