In a case of hematuria of glomerular origin, urine examination shows the presence of all of the following except:
Correct Answer: Acanthocytes
Description: In hematuria of glomerular origin red cell cast, crenated red cells and dysmorphic red cells are present. RBC cast represent blood and protein derived from the glomerulus and always indicate glomerulonephritis. Presence of dysmorphic red cells under phase contrast microscopy is also highly suggestive of a glomerular origin of red cells. Acanthocytes are deformed erythrocytes with spicules. Thorny erythrocytes are seen in 3 hereditary neurologic syndromes such as abetalipoproteinemia, neuroacanthocytosis and Mc Leod syndrome. Ref: Laboratory Medicine in Psychiatry and Behavioral Science By Sandra A. Jacobson, Chapter 335
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