Drug of Choice for Digoxin induced Ventricular Tachycardia
Correct Answer: Lignocaine
Description: * Lignocaine is the drug of choice for Digoxin induced Ventricular Tachycardia. * Digoxin, a cardiac glycoside - used in treatment of hea failure and in control of ventricular rate in atrial fibrillation/flutter. * It has low margin of safety and high toxicity index. (Therapeutic Index: 1.5-3). * About 25% of patients on Digoxin therapy develop toxicity features. * Digoxin toxicity can induce almost any cardiac dysrrhythmia except rapidly conducted atrial arrhythmias like atrial flutter and atrial fibrillation. Mobitz type II AV block is also a rare phenomenon in digoxin toxicity. Second-degree AV block (Type 2) is usually caused by structural damage to the distal conduction system located in the ventricular poion of the myocardium- linked to an infarction/idiopathic Fibrosis/cardiac surgery/ infections/ inflammations/ auto-immune disease. * Digoxin- specific Fab antibody is a specific antidote for Digoxin Overdosage. (~40mg of Fab = 1mg Digoxin ). Ref:- KD Tripathi Essentials of Medical Pharmacology 8th Ed; Pg num:- 560
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now