Select the false statement among the following?
Correct Answer: Loading dose is equal to Vd divided by target plasma concentration
Description: * Lipid soluble drugs (nonpolar) have high volumes of distribution than drugs which are more polar* Volume of distribution may be increased in renal failure & hepatic failure due to fluid retention, altered body fluid. However high plasma protein binding reduces the Vd. Loading dose = volume of distribution x target plasma concentration Maintenance dose = clearance x target plasma concentration T 1/2 is constant in first order kinetics T 1/2 is directly propoional to plasma concentration in zero order kinetics Clearance is indirectly propoional to plasma concentration
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now