Which of the following is the complimentary sequence of 5′ TTAAGCTAC 3′?

A. 5' GTACGCTTAA 3'

B. 5' AATTCGCATG 3'

C. 5' CATGCGAATT 3'

D. 5' TTAAGCGTAC 3'

Correct Answer: 5' GTACGCTTAA 3'

Description: The complementary sequence of 5' TTAAGCTAC 3' is 3'AATTCGCATG 5'or 5' GTACGCTTAA 3'. Complementary sequence of 5'-3' end always proceeds from 3'- 5. In the double stranded DNA, the bases of one strand of DNA pairs with the bases of the second strand in such a way that Adenine (A) always pairs with Thiamine (T) and Cytosine (C) always pairs with Guanine (G). Ref: Harper Illustrated Biochemistry, 26th Edition, Chapter 35, Page 303 ; Lippincott's Illustrated Reviews: Biochemistry, 3rd Edition, Chapter 29, Page 395

Category: Biochemistry

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