Virilisation of the female is present in all, EXCEPT
Correct Answer: 17-α hydroxylase deficiency
Description: Congenital adrenal hyperplasia -
Is commonly caused by following 3 enzyme deficiencies
21 α hydroxylase deficiency (complete)
21 α hydroxylase deficiency (partial)
11 α Hydroxylase deficiency
17 α hydroxylase deficiency
17 α hydroxylase deficiency
Hypertension
No virilization in females (because the gene that codes for 17 α also codes for the enzyme in adrenal cortex).
Primary amenorrhoea and failure of development of secondary sexual characteristic in females.
Male pseudohermaphrodites
21 α hydroxylase deficiency Complete (Salt losing virilizing syndrome)
Hypotension
Virilization (& Precocious puberty in males)
21α hydroxylase deficiency Partial (Simple virilizing)
Normal B.P.
Virilization (& Precocious puberty in males)
11 β hydroxylase deficiency
Hypertension
Virilization (& Precicous puberty in males)
Category:
Medicine
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