True statement regarding development of drug resistance in MRSA is?
Correct Answer: Occurs due to change in penicillin blinding proteins
Description: MRSA have emerged in many areas. These are insensitive to all penicillinase-resistant penicillins and to other beta-lactams as well as to erythromycin, aminoglycosides, tetracyclines, etc. The MRSA have altered PBPs which do not bind penicillins. ESSENTIALS OF MEFICAL PHARMACOLOGY page no 721
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