Which of the following antigens are associated with cicatricial pemphigoid?
Correct Answer: BPAG2 and epiligrin
Description: Cicatricial Pemphigoid:
Autoimmune blistering disease associated with autoantibodies directed against basement membrane zone target antigens.
Autoantibodies of IgG subclass, particularly IgG4, are associated with CP.
IgA antibodies have also been detected.
The two major antigens associated with CP are bullous pemphigoid antigen 2(BPAG2) and epiligrin (laminin-5).
Category:
Pathology
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