Drugs causing macular toxicity when given intravitreally?
Correct Answer: Gentamycin
Description: (Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 445)Intravitreal aminoglycosides (gentamycin, amikacin) are a repoed cause of macular toxicityAminoglycosides induced macular toxicity is thought to be paially due to the gravity-induced settling of drugs on the macula in the supine positionThis may result in a higher concentration of drug locally at the macula.
Category:
Ophthalmology
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