Most commonly associated mutation in prostratic carcinoma is?
Correct Answer: GPST 1
Description: Harshmohan textbook of pathology 7th edition. prostatic carcinoma- at genetic level following epigenetic phenomenon and acquired somatic mutation have been repoed in development of prostatic carcinoma. 1. Epigenetic phenomenon- hyper methylation of GSTP 1 gene promoter causing loss of function of the gene that detoxifyes carcinogens. .
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