Most common ophthalmological manifestations of the X-linked form of Alpo syndrome is:
Correct Answer: Dot and flake retinopathy
Description: The typical ophthalmological manifestations of the X-linked form of AS are 1. Dot-and-fleck retinopathy which occur in about 85% of affected adult males And 2. Anterior lenticonus which occur in about v25% Other additional ocular abnormalities are: 1. Recurrent corneal epithelial erosions 2. Posterior polymorphous corneal dystrophy 3. Posterior lenticonus 4. Macular holes 5. Retinal detachment The ocular manifestations presents after renal abnormalities manifest The dot-and-fleck retinopathy is not associated visual impairment or night blindness. Ref: Dan Med Bull 2009;56:105-52
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