Hemolysis in G6PD may be caused by all except
Correct Answer: Primaquine
Description: Ref Harrison 19 th ed pg 656 Although it was primaquine (PQ) that led to the discovery of G6PD deficiency, this drug has not been very prominent subsequently, because it is not necessary for the treatment of life-threatening P. falciparum malaria. Today there is a revival of interest in PQ because it is the only effective agent for eliminating the gameto- cytes of P. falciparum (thus preventing fuher transmission) and eliminating the hypnozoites of Plasmodium vivax (thus preventing endogenous relapse). In countries aiming to eliminate malaria, there may be a call for mass administration of PQ; this ought to be associ- ated with G6PD testing. At the other end of the historic spectrum, the latest addition to the list of potentially hemolytic drugs
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