Which of the following seen in Psoriasis –
Correct Answer: munro's micro abscess
Description: <p>PSORIASIS:-<p>PSORIASIS:-Inflammatory skin disease.Genetic predisposition. Psoriasis susceptibility 1 (PSORS1) is the most impoant susceptibility locus. Clinical features:-1. Classic lesion-Well defined erythematous plaque with a silvery white scales.2. Size varies from pin point papules to plaques. Histopathology:-1. Hyperkeratosis 2. Parakeratosis- retention of nuclei3. Munro's microabscess in stratum corneum focal collection of neutrophils in stratum corneum4. Spongiform pustules of kogoj- collection of neutrophils in malpighian layer.5. Absence of granular layer.6. Regular elongation of rete ridges with branches and clubbing CAMEL FOOT APPEARENCE7. Thinning of suprapapillary epidermis 8. Elongation of dermal papillae with dilated and touous capillaries . IADVL textbook of dermatology page 1041
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