Lactate is formed in all except –
Correct Answer: Brain
Description: Ans. is 'c' i.e., Braino Lactate is formed in anaerobic glycolysis.o Brain utilizes glucose only aerobically (there is no anaerobic glycolysis).o Anaerobic glycolysis: - It occurs in the absence of oxygen. The pyruvate is fermented (reduced) to lactate in single stagedQ The reoxidation of NADH (formed in the glvceraldehyde-3-phosphate dehydrogenase step) by respiratory- chain is prevented as same NADH is utilized at lactate dehydrogenase step. So, there is no net production of NADH. Thus, there is net gain of 2 ATP only. Unlike pyruvate which is converted to acetyl Co A to enter into krebs cycle, lactate cannot be further utilized by further metabolic pathways. Thus, lactate can be regareded as dead end in glycolysisQ. Anaerobic glycolysis occurs in exercising skeletal muscle, RBCs, lens, some region of retina, renal medulla, testis and leucocytes.
Category:
Biochemistry
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