Which of the following is a Polygenic disorder:
Correct Answer: Hypertension
Description: d. Hypertension(Ref: Nelson's 20/e p 650, Ghai 8/e p 643)Polygenic disorders:Disorders caused by interactions between variant forms of genes and environmental factors.Occur when many polymorphisms, each with a modest effect and low penetrance, are co-inheritedE.g. HypertensionQ, Diabetes mellitus, Coronary Artery disease, Septal DefectsQ, Cleft lip
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Pediatrics
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