Break bone fever is caused by ?

Correct Answer: Dengue fever
Description: Ans. is 'c' i.e., Dengue fever Break bone fever (Saddle back fever) is caused by dengue virus. Dengue fever Dengue fever is caused by arboviruses (at least 4 serotypes have been recognized) It is transmitted by Aedes (Aedes aegypti is the main vector). The reservoir of infection is both man and mosquito. The transmission cycle is Man-mosquito-man Dengue fever occurs both epidemically and endemically. Epidemics stas in rainy season and are usually explosive. Aedes mosquito becomes infective by feeding on a patient from the day before onset to the 5th day of illness. Various manifestations of Dengue infection A) Classical dengue fever - Also known as break bone fever Incubation period 2-7 days (3-10 days -4 Park) Onset is sudden with chills and fever. Fever is usually between 39degc and 40degc temperature returns to normal after 5-6 days or subside on about the 3rd day and rise again after 5-8 days after onset (saddle back fever). Rashes appear in 80% of cases during remission or during second febrile phase. The rash lasts for 2 hours to several days and may be followed by desquamation. B) Dengue Hemorrhagic fever (DHF)- It is a severe form of dengue fever caused by infection with more than one dengue virus. The severe illness is thought to be due to double infection with more than one dengue virus. Dengue hemorrhagic fever is believed to result from reinfection with a virus of different serotype ( due to enhancing antibodies) DHF usally occurs after sequential infection with any two of the four serotypes of dengue virus. Sequence of infection may be impoant; serotype 1 followed by serotype2 is more dangerous than serotype 4 followed by serotype 2.
Category: Microbiology
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