Which of the following methods can be used to detect rubella infection in children –
Correct Answer: IgM antibody in fetal blood
Description: Ans. is 'c' i.e., IgM antibody in fetal blood Laboratory diagnosis o Isolation of virus in cell cultures of throat samples, urine or other secretions. o Normally, maternal rubella antibodies in the form of IgG is transferred to infants and is gradually last over a period of 6 months. Persistent beyond 1 year in an unvaccinated child suggests the diagnosis of congenital rubella. o Presence of Ig M antibodies is diagnostic. o PCR for rubella RNA.
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Pediatrics
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