A 30 year old patient on digoxin therapy has developed digitalis toxicity. The plasma digoxin level is 4 ng/ml. Renal function is normal and the plasma t1/2 for digoxin in this patient is 1.6 days. How long should you withhold digoxin in order to reach a safer yet probably therapeutic level of 1 ng/ml?
Correct Answer: 3.2 days
Description: * We want to decrease the plasma concentration of digoxin from 4 ng/ml to 1 ng/ml. * It will take two half lives (From 4 ng/ml to 2 ng/ml in one half life and from 2 ng/ml to 1 ng/ml in second half life). * Thus time required will be 2 x t 1/2 i.e. 2 x 1.6 = 3.2 days.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now