Symptoms of Hanup’s disease mimic:-
Correct Answer: Pellagra
Description: Deficiency of tryptophan will lead to the deficiency of Niacin in the body Thus causing pellagra like symptoms (neurological and dermatologic), Hanup's Disease: AR (autosomal recessive), rare disorder Defect in neutral amino acid transpoer also called mono-amino mono carboxylic amino acid transpoer which transpos neutral amino acid including tryptophan. Failure to absorb tryptophan from intestine and also reabsorb it by kidneys Tryptophan forms Niacin (Vitamin B3) in the body, Deficiency of it will lead to the deficiency of Niacin in the body Thus causing pellagra like symptoms (neurological and dermatologic),despite an adequate intake of both Tryptophan and niacin. C/F - Aminoaciduria i.e. Tryptophan in urine without a corresponding increase in plasma tryptophan levels
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now