Low dose dopamine (1-2 mcg/kg) result in
Correct Answer: Dilatation of renal vasculature
Description: At low concentrations, the primary interaction of dopamine is with vascular D1 receptors, especially in the renal, mesenteric, and coronary beds-leads to vasodilation Higher concentrations, dopamine exes a positive inotropic effect on the myocardium, acting on beta-1 adrenergic receptors. At more than 10 mcg/kg/min rate of infusion, dopamine can stimulate alpha 1 receptors leading to peripheral vasoconstriction Dopamine also causes the release of norepinephrine from nerve terminals, which contributes to its effects on the hea. DOSE DEPENDENT EFFECTS OF DOPAMINE Dose Rate Receptors stimulated Major action Low dose 1-2 mcg/kg/min D1 Renal vasodilation Intermediate dose 2-10 mcg/kg/min D1 & Beta 1 Cardiac stimulation High dose > 10 mcg/kg/min D1, Beta 1 and Alpha 1 Vasoconstriction
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now