A 50 year old man presents with paresthesia. Hb = 6.8 gms/dl. Peripheral smear shows macrocytes and neutrophis with hypersegmented nuclei. Endoscopy reveals atroghic gastritis. Which of the following deficiency is more likely?

Correct Answer: Vitamin B12 deficiency
Description: above clinical features point towards Vit B12 deficiency due to Pernicious anemia. Pernicious anemia -Type II Hypersensitivityin which ABs are formedagainst intrinsic factorthus inhibits the binding of IF+B12. Intrinsic factor deficiency-Malabsorption of vitamin B12 - Megaloblastic anemia /Pernicious anemia
Category: Physiology
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