Which of these drugs DO NOT decrease angiotensin Il activity
Correct Answer: Nesiritide
Description: (Ref: Katzung 10/e p205, 286) ACE inhibitors and AT1, antagonists decrease angiotensin Il activity. Omapatrilat is a vasopeptidase inhibitor that acts by inhibiting two enzymes, ACE and NEP. As it inhibits ACE, it may also decrease angitotensin II activity. Nesiritide is a recombinant BNP and has no effect on angiotensin II activity.
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